How to treat Depression when taking Sumatriptan Injections

Hi all

Does anyone know which antidepressants can be use with sumatriptan ?

I've just statred to have CH attacks after at least a 2 year gap from Full Blown attacks.... and was due to strart on ssri. But concerned about the serotonin syndrome.

Does anyone have any knowledge ?

Thanks

Roger

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Val

Joined: Wed, 15/04/2026 - 17:47

Last seen: 5 months

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Submitted by Val on Fri, 04/02/2022 - 14:29

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Hello Roger,

I'd suggest that you talk to your neuro, or headache nurse, or maybe a pharmacist to discuss this. The contra-indications on sumatriptan are both MAOI's and SSRI's. We can't really advise on which are best [if any] as we don't know your health history and we are not heallth professionals. So it is the health professionals you need to speak to.

Hope you get sorted out!

Val.