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New research 877: Orgasmic SUNCT and topiramate?

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#1 Thu, 25/09/2014 - 12:54
PeterM
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Joined: 21/03/2012 - 15:17

New research 877: Orgasmic SUNCT and topiramate?

Headache. 2014 Sep 24. doi: 10.1111/head.12445. [Epub ahead of print]

An Unusual Case of Episodic SUNCT Responding to High Doses of Topiramate.

Khalil M1, Maniyar F, Ahmed F.

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Abstract

Trigeminal autonomic cephalalgias (TAC) are rare. Cluster headaches comprise the majority, with short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) being the rarest and shortest in duration. The majority of SUNCT are primary with a few cases occurring secondary to posterior fossa or pituitary lesions. Although activities like exercise or blowing of the nose can trigger SUNCT, onset during orgasm has not been described. Short-lasting aura has been described in TACs including SUNCT, but persistence of focal symptoms and signs without an underlying structural lesion have not been described. Lastly, treatment of SUNCT is difficult, with lamotrigine being the most common effective reported. We report a case of episodic SUNCT with symptoms suggestive of brainstem stroke that completely resolved spontaneously for which no underlying structural cause was found. The onset of first attack occurred during orgasm, and the patient responded to a high dose of topiramate.

ATB
P.

Fri, 10/04/2015 - 09:32
bobtyler2
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Last seen: 5 years 6 months ago
Joined: 08/04/2015 - 16:18

HI IS TOPIRAMATE STRONGER THAN LACMOTRIGINE300  LACOMIDE 200 SPREGABLIN300  ALL TO GETHER.TWICE DAILY BOB.

not sure about how things work ?
sunct is my problem.

Sat, 11/04/2015 - 12:40
Val
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Last seen: 5 days 7 hours ago
Joined: 21/03/2012 - 15:16

Hi Bob

That's something only a pharmacist could answer, we're not health professionals on here, so really it's better to ask 'them that know'.  It does sound a hell of a mixture though!

Val.

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